Esta buscando: psip1

Numero del catalogo: (BOSSBS-1282R-A680)

Proveedor: Bioss

Descripción: iASPP (inhibitor of apoptosis stimulating protein of p53, RelA-associated inhibitor (RAI), NFKap B-interacting protein 1, protein phosphatase 1 regulatory subunit 13-like, PPP1R13L) is the third member of the ASPP family of proteins. Unlike ASPP1 and ASPP2, which interact with p53 and enhance its ability to induce apoptosis, iASPP inhibits apoptosis induced by p53 overexpression. iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA),3 interacts with NFKap B in vivo, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles. iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia. Alternate Names: apoptosis stimulating protein of P53 1; Apoptosis-stimulating of p53 protein 2; Tumor suppressor p53-binding protein 2; p53-binding protein 2; p53BP2; 53BP2; Bcl2-binding protein; Bbp; Renal carcinoma antigen NY-REN-51.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-11549R-A647)

Proveedor: Bioss

Descripción: Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-11549R-A488)

Proveedor: Bioss

Descripción: Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-15164R-A488)

Proveedor: Bioss

Descripción: C3IP1

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-2735R-A647)

Proveedor: Bioss

Descripción: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1-chloro-2,4-dinitrobenzene. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity).

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-5226R-HRP)

Proveedor: Bioss

Descripción: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-13229R-A680)

Proveedor: Bioss

Descripción: FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2 and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-8191R-A750)

Proveedor: Bioss

Descripción: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-5226R-A555)

Proveedor: Bioss

Descripción: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (ABCAAB321320-100UL)

Proveedor: Abcam

Descripción: Anti-PARP1 Rabbit Monoclonal Antibody [clone: EPR18461] (Alexa Fluor® 750)

UOM: 1 * 100 µl

New Product Promoción

Numero del catalogo: (BOSSBS-15164R-HRP)

Proveedor: Bioss

Descripción: C3IP1

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (USBI031528-FITC)

Proveedor: US Biological

Descripción: Anti-ASIC1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (USBI039713-FITC)

Proveedor: US Biological

Descripción: Anti-PBXIP1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (USBI039620-AP)

Proveedor: US Biological

Descripción: Anti-PAIP2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (USBI039669-FITC)

Proveedor: US Biological

Descripción: Anti-PARP1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (USBI034292-HRP)

Proveedor: US Biological

Descripción: Anti-CSPP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

Promoción