Esta buscando: STEMCELL Technologies

Numero del catalogo: (STMC07005)

Proveedor: STEMCELL Technologies

Descripción: Support cell attachment, growth, and proliferation with CellAdhere™ Type I Collagen, Human, Lyophilised. The most abundant type of collagen in the human body, type I collagen is a natural extracellular matrix protein that provides structural support and mimics physiological conditions, making it an ideal cultureware coating surface to support cell attachment in 2D applications.

UOM: 1 * 15 mg

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Numero del catalogo: (STMC19657)

Proveedor: STEMCELL Technologies

Descripción: Immunomagnetic isolation of circulating tumor cells directly from whole blood

UOM: 1 * 1 KIT

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Proveedor: STEMCELL Technologies

Descripción: Rat monoclonal IgM antibody against mouse CD49b (integrin α2), biotin-conjugated.

Numero del catalogo: (STMC03816)

Proveedor: STEMCELL Technologies

Descripción: Serum-free, animal component-free semi-solid medium with supplements for selection and cloning of transfected CHO cells.

UOM: 1 * 90 mL

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Numero del catalogo: (STMC84435)

Proveedor: STEMCELL Technologies

Descripción: Methylcellulose-based medium with recombinant cytokines. 1×100 ml bottle.

UOM: 1 * 100 mL

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Numero del catalogo: (STMC60108PS)

Proveedor: STEMCELL Technologies

Descripción: Mouse monoclonal IgG2a, kappa isotype control antibody, PerCP-Cy5.5-conjugated.

UOM: 1 * 100 µG

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Numero del catalogo: (STMC60074AD)

Proveedor: STEMCELL Technologies

Descripción: Rat monoclonal IgM, kappa isotype control antibody, Alexa Fluor® 488-conjugated.

UOM: 1 * 25 µG

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Proveedor: STEMCELL Technologies

Descripción: Fibroblast growth factor 10 (FGF-10) is a member of the fibroblast growth factor (FGF) family predominantly expressed by mesenchymal fibroblasts during embryonic development (Emoto <i>et al.</i>; Igarashi <i>et al.</i>). It binds with high affinity to fibroblast growth factor receptor 2-IIIb (FGFR2-IIIb), and also has a weaker affinity for FGFR1-IIIb (Beer <i>et al.</i>). FGF-10 and FGF-7 have similar receptor binding properties and target cell specificities but are differentially regulated by components of the extracellular matrix (Emoto <i>et al.</i>; Igarashi <i>et al.</i>). FGF-10 has been shown to mediate epithelial-mesenchymal interactions, which are essential to lung development (Sekine et al; Ware and Matthay). FGF-10 also has a role in mobilisation and proliferation of lung-resident mesenchymal stem cells (MSCs) and protection and repair against acute lung injury (Tong <i>et al.</i>; Ware and Matthay), as well as endodermal differentiation of human pluripotent stem cells to insulin-producing pancreatic-like cells (Takeuchi <i>et al.</i>).

Proveedor: STEMCELL Technologies

Descripción: Neurotrophin-4 (NT-4) is a member of the nerve growth factor family which includes neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF), all of which promote the differentiation, growth, and survival of peripheral and central nervous system neurons (Eide <i>et al.</i>). NT-4 binds and activates tropomyosin receptor kinase B (TrkB) at the cell surface; in doing so, it acts as a survival factor for certain populations of sensory neurons (Berkemeier <i>et al.</i>; Skaper). It has been shown that NT-4, together with BDNF, promotes neurite extension and maturation, as well as maintenance of differentiated cerebellar granule cells (Gao <i>et al.</i>).

Proveedor: STEMCELL Technologies

Descripción: Interleukin 17A (IL-17A) is the founding member of the family of cytokines that includes IL-17B through IL-17F. It is a potent pro-inflammatory cytokine that plays a key role in defense against pathogens. IL-17A and IL-17F signal as homodimers or heterodimers through the same receptor, and activate NF-κB, MAPK, and C/EBP pathways (Gaffen). IL-17A is produced by Th17 cells, CD8+ T cells, γ/δ T cells, natural killer (NK) T cells, B cells, innate lymphoid cells, and mesenchymal stromal cells (MSCs) (Cua and Tato; Gaffen; Mojsilović <i>et al.</i>). IL-17A mediates protection against extracellular pathogens, and together with IL-22 stimulates production of antimicrobial peptides. It induces granulopoiesis factors and neutrophil-specific chemokines. Together with tumor necrosis factor alpha (TNF-α), IL-17A induces a sustained neutrophil recruitment during inflammation (Cua and Tato). IL-17A receptor is expressed at particularly high levels on stromal cells, including MSCs. IL-17A increases the frequency and the average size of fibroblast colony-forming units (CFU-F), as well as the proliferation of marrow-derived MSCs. It enhances osteogenic differentiation, and inhibits adipocyte differentiation and chondrogenesis (Mojsilović <i>et al.</i>).

Proveedor: STEMCELL Technologies

Descripción: Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, unconjugated.

Proveedor: STEMCELL Technologies

Descripción: Mouse monoclonal IgG3, kappa isotype control antibody, PE-conjugated.

Proveedor: STEMCELL Technologies

Descripción: Hamster (Armenian) monoclonal IgG1 antibody against mouse CD3e, APC-conjugated.

Proveedor: STEMCELL Technologies

Descripción: RANTES (regulated upon activation, normal T cell expressed and secreted), also known as CCL5, is a member of the CC family of chemokines and is able to recruit leukocytes to sites of inflammation (Schall <i>et al.</i>). RANTES is secreted by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells (Aldinucci and Colombatti; Soria and Ben-Baruch). This chemokine exerts its effect by interacting with the chemokine receptors CCR1, CCR3, CCR4, and CCR5. RANTES plays an active role in recruiting a variety of leukocytes into inflammatory sites, including T cells, macrophages, eosinophils, and basophils. In collaboration with certain cytokines that are released by T cells such as IL-2 and IFN-γ, RANTES also induces the activation and proliferation of NK cells to generate CC chemokine-activated killer cells, which are highly cytolytic (Lv <i>et al.</i>; Maghazachi <i>et al.</i>). It has been shown that RANTES produced by CD8+ T cells inhibits HIV infection of primary human peripheral blood mononuclear cells (Appay and Rowland-Jones; Cocchi <i>et al.</i>).

Proveedor: STEMCELL Technologies

Descripción: Nerve growth factor (NGF)-beta is a prototypical member of the neurotrophin family and has a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and neuron migration. The beta subtype of NGF is biologically active in comparison to the alpha-2 and gamma-2 subtypes. NGF-beta in its secreted form can bind to tyrosine kinase A (TrkA) receptor with high affinity and to p75 (NTR) with low affinity (Levi and Alemà; Sofroniew <i>et al.</i>). NGF has been shown to possess pro-inflammatory and pro-fibrogenic properties (Micera <i>et al.</i>). It has also been shown that overexpression of NGF-beta promotes differentiation of bone marrow mesenchymal stem cells into neurons through regulation of AKT and MAPK pathways (Yuan <i>et al.</i>).

Numero del catalogo: (STMC60018)

Proveedor: STEMCELL Technologies

Descripción: Mouse monoclonal IgG1 antibody against human, chimpanzee CD45, unconjugated.

UOM: 1 * 100 µG

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