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Product Image-SCOT241882703

Frascos, fondo redondo, con dos conexiones laterales inclinadas y juntas de tierra estándar, DURAN®

Proveedor: DWK Life Sciences
Descripción: DURAN®, vidrio de borosilicato 3.3, transparente.

Product Image-PRSI32-129

Anti-CD19 Mouse Monoclonal Antibody

Numero del catalogo: (PRSI32-129)
Proveedor: ProSci Inc.
Descripción: The CD19 antigen (95 kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.
UOM: 1 * 100 µG
Image Unavailable-SHANA78710013

Accessories for Cytospin™ 4 cytocentrifuge

Numero del catalogo: (SHANA78710013)
Proveedor: Epredia
Descripción: EZ funnel starter kit, includes 25 EZ Megafunnels™, 20 EZ single white Cytofunnels®, 20 EZ double cytofunnels and Cytoslides®, Centrífuga de sobremesa
UOM: 1 * 1 UN
Product Image-521-1156

Centrífugas de sobremesa con ventilación/refrigeración ROTINA 420/420R

Proveedor: Hettich
Descripción: High performance, compact centrifuges developed for high sample throughput as well as for high sample volumes.

Environmentally Preferable

Image Unavailable-ICNA0210264801

Ftalaldehído ≥98%, yellow crystals

Proveedor: MP Biomedicals
Descripción: The molecule is a dialdehyde, consisting of two formyl (CHO) groups attached to adjacent carbon centres on a benzene ring.

Product Image-SOVEC10141037

Height adjustable worktable

Proveedor: TRESTON
Descripción: These worktables are a suitable solution for industrial laboratories and research and development centers. They are designed to accommodate the necessary measurement equipment and other tools ergonomically at a safe distance for use. These laboratory benches fit also to education purposes. Modularity and accessories are individually adjustable according the task and human requirements.

Product Image-531-9133

Flasks, round bottom, glass, clear, with spherical joints

Proveedor: witeg Labortechnik
Descripción: Borosilicate glass 3.3, plastic coated.

Product Image-PRSI26-330

Anti-MAP4K2 Rabbit Polyclonal Antibody

Numero del catalogo: (PRSI26-330)
Proveedor: ProSci Inc.
Descripción: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
UOM: 1 * 50 µG
Product Image-LENZ03348449

Flasks, round bottom with four necks and standard ground joints, side necks angled (15°)

Proveedor: LENZ, E. (Lenz Laborglas GmbH & CO.KG)
Descripción: DURAN®, borosilicate glass, clear.

Product Image-BRND137615

Imanes de agitación, PTFE, octogonales, con anillo central

Proveedor: Brand
Descripción: These octagonal shaped PTFE magnetic stirrer bars are ideal for vessels with slightly uneven bottoms. The angular surface creates high turbulence even at low speeds.

Image Unavailable-BOSSBS-2734R-A750

Anti-Bcl6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numero del catalogo: (BOSSBS-2734R-A750)
Proveedor: Bioss
Descripción: Transcriptional repressor mainly required for germinal centre (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
UOM: 1 * 100 µl
Product Image-DIVERESE-C050

Refrigeradores para depósitos de reactivos

Proveedor: DIVERSIFIED BIOTECH
Descripción: Estos refrigeradores de sobremesa se colocan bajo los depósitos y mantienen los reactivos a ~5 °C durante aproximadamente 3 horas.

Product Image-WITG0.700.100

Flasks, round bottom, with two necks

Proveedor: witeg Labortechnik
Descripción: Borosilicate glass 3.3.

Image Unavailable-BOSSBS-0087R-CY5

Anti-CASP3 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-0087R-CY5)
Proveedor: Bioss
Descripción: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
UOM: 1 * 100 µl
Product Image-115-1880

Estera de banco de preparación de quimioterapia estéril, BioClean ChemPrep ™

Proveedor: Nitritex
Descripción: La esterilla de preparación de quimioterapia estéril de BioClean es altamente absorbente.

Certificados

Product Image-552-0034

Chromatogram immersion device for TLC plates

Proveedor: CAMAG
Descripción: This chromatogram immersion device is suitable for TLC and HPTLC plates up to 200×200 mm.

Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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