Esta buscando: DOMNICK+HUNTER

Numero del catalogo: (BC92)

Proveedor: G-Biosciences

Descripción: This sulpho-SHPP (water-soluble Bolton-Hunter Reagent) is designed to aid the labelling of proteins with radioactive iodine. Radioactive iodine (¹²⁵I) is routinely used by researchers to label proteins. The iodination of proteins can be performed enzymatically or chemically.

UOM: 1 * 100 mg

Promoción

Proveedor: Apollo Scientific

Descripción: Bolton-Hunter reagent (sulpho-SHPP)

Proveedor: Apollo Scientific

Descripción: Bolton-Hunter reagent (sulpho-SHPP), grado técnico

Numero del catalogo: (J64508.03)

Proveedor: Thermo Fisher Scientific

Descripción: Bolton-Hunter reagent (sulpho-SHPP)

UOM: 1 * 1 g

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Numero del catalogo: (PIER27712)

Proveedor: Thermo Fisher Scientific

Descripción: Sulpho-SHPP, sulphosuccinimidyl-3 -(4-hydroxypheynyl) propionate, also known as water-soluble Bolton-Hunter reagent, conjugates tyrosine-like functional groups to primary amines to increase the number of tyrosyl groups that can be iodinated by iodine-125 labeling procedures.

UOM: 1 * 100 mg

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Numero del catalogo: (DHUN110H-MDCARRIER)

Proveedor: DOMNICK HUNTER

Descripción: Parker Domnick Hunter hydrogen generators produce a continuous flow of pure hydrogen from deionised water. These hydrogen generators provide a safe and hassle-free alternative to high pressure gas cylinders. Hydrogen is only generated on demand at low pressure and the volume of stored gas is minimal.

UOM: 1 * 1 UN

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Proveedor: Avantor Fluid Handling

Descripción: Advanced airflow technology makes this the most energy efficient compressed air filtration system available.

Numero del catalogo: (232-0063)

Proveedor: HAMMACHER KARL

Descripción: Splinter forceps with lancet tips.

UOM: 1 * 1 UN

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Numero del catalogo: (633-0221)

Proveedor: Lovibond Tintometer

Descripción: Serie de colorímetros espectrofotométricos para la gradación de colores de muestras transparentes. Cada versión del PFX<i>i </i>195 incluye una selección de escalas de color estándar que se utiliza en un sector de actividad específico. Se pueden añadir escalas adicionales, en el momento del pedido o posteriormente, como actualizaciones opcionales para proporcionar la flexibilidad que satisfaga sus necesidades individuales. Los resultados también se pueden mostrar en términos de datos espectrales y valores CIE. Para los tipos de productos incompatibles con las escalas de color estándar, el software de PFX<i>i </i>195 permite a los usuarios desarrollar una escala personalizada a partir de una serie de muestras de referencia y obtener la correspondencia más cercana a la referencia almacenada.

UOM: 1 * 1 UN

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Numero del catalogo: (MMMAMT13H222A)

Proveedor: 3M

Descripción: [EN]EARMUFF PELTOR PROTAC HUNTER GREEN 1 * 1 UN

UOM: 1 * 1 UN

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Numero del catalogo: (PRSI56-193)

Proveedor: ProSci Inc.

Descripción: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

UOM: 1 * 400 µl

Promoción

Numero del catalogo: (BOSSBS-6580R)

Proveedor: Bioss

Descripción: Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-6580R-HRP)

Proveedor: Bioss

Descripción: Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (PRSI50-221)

Proveedor: ProSci Inc.

Descripción: It is well known that the control of gene expression involves activation of protein kinase cascades that regulate transcription factors within the nucleus (Karin and Hunter, 1995). The cyclic AMP response element binding protein (CREB) is one of the best characterized stimulus-induced transcription factors (Montminy, 1997). This transcription factor is a component of intracellular signaling events that regulate a wide range of biological functions, from spermatogenesis to circadian rhythms and memory (Shaywitz and Greenberg, 1999; Silva et al., 1998). A variety of protein kinases including protein kinase A (PKA), mitogenactivated protein kinases (MAPKs), and Ca2+/calmodulin-dependent protein kinases (CaMKs) phosphorylate CREB at serine 133 (Ser133), and phosphorylation of Ser133 are required for CREB-mediated transcription (Johannessen et al., 2004; Kornhauser et al., 2002).

UOM: 1 * 100 µl

Promoción

Proveedor: DOMNICK HUNTER

Descripción: Kit de mantenimiento de 4.000 horas para todos los LCMS

Numero del catalogo: (STMC78083.1)

Proveedor: STEMCELL Technologies

Descripción: Interleukin 6 receptor (IL-6R) alpha is a type I transmembrane glycoprotein that forms a complex with type I transmembrane signal transducer protein gp130 (CD130) and mediates the biological activities of IL-6. IL-6 binds to the membrane-bound non-signaling IL-6R alpha (mIL-6R), and the complex binds to two molecules of gp130 and leads to ‘classical’ IL-6-signal transduction, which includes activation of JAK/STAT, ERK, and PI3K signal transduction pathways (Scheller <i>et al.</i>). In contrast, a soluble form of IL-6R alpha (sIL-6R), which comprises the extracellular portion of the receptor, binds to the secreted IL-6 to form a complex that promotes bioavailability of IL-6. The complex of IL-6 and sIL-6R can bind to gp130 on cells that do not express the IL-6R and are unresponsive to IL-6. This process is known as trans-signaling (Hunter and Jones; Rose-John S). sIL-6R regulates both local and systemic IL-6-mediated events. Elevated levels of sIL-6R have been documented in several disease conditions such as rheumatoid arthritis, myeloma, and Crohn’s disease (Jones <i>et al.</i>; Mihara <i>et al.</i>).

UOM: 1 * 50 µG

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