Esta buscando: Nicotine+ditartrate+dihydrate

Proveedor: Cayman Chemical

Descripción: Aminophylline is a competitive and non-selective phosphodiesterase inhibitor (IC₅₀=120 µM) and adenosine receptor antagonist. It is a complex of theophylline and ethylenediamine that has <i>in vivo</i> bronchodilator and vasodilator effects.

Numero del catalogo: (PRSI25-900)

Proveedor: ProSci Inc.

Descripción: SLC22A13 is a member of the organic-cation transporter family. SLC22A13 is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems.

UOM: 1 * 50 µG

Promoción

Numero del catalogo: (BSBTPB10009)

Proveedor: Boster Bio

Descripción: Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme that in humans is encoded by the PBEF1 gene. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

UOM: 1 * 100 µG

Promoción

Proveedor: MP Biomedicals

Descripción: Quinine Hemisulfate is an alkaloid originally isolated from the Cinchona family of South American trees. It is an antimalarial agent, anticholinergic, antihypertensive and hypoglycemic agent.

Proveedor: Thermo Fisher Scientific

Descripción: Trehalose, dihydrate, is an inducer of autophagy, it protect cells against numerous environmental stresses. It is seldom used as a direct replacement for conventional sweeteners. Used as a cryoprotectant in a variety of cell freezing media.

FDS Certificados

Numero del catalogo: (ICNA0520342901)

Proveedor: MP Biomedicals

Descripción: Alizarina complexona

UOM: 1 * 1 g

Promoción

Proveedor: Thermo Fisher Scientific

Descripción: di-Sodio tetraborato, anhidro 98% para análisis

FDS

Numero del catalogo: (PRSI27-667)

Proveedor: ProSci Inc.

Descripción: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

UOM: 1 * 100 µG

Promoción

Proveedor: Honeywell Chemicals

Descripción: Alizarina complexona ∼85% for the determination of fluorine, Fluka™

Numero del catalogo: (PRSI27-668)

Proveedor: ProSci Inc.

Descripción: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

UOM: 1 * 50 µG

Promoción

Proveedor: MP Biomedicals

Descripción: Borax anhydrous typically used as a buffer component.

Numero del catalogo: (STMC100-1335)

Proveedor: STEMCELL Technologies

Descripción: Use visfatin to catalyse the production of nicotinamide mononucleotide from nicotinamide (Revollo <i>et al.</i>). Nicotinamide mononucleotide is a precursor to nicotinamide adenine dinucleotide (NAD) that is vital to energy metabolism, cell death, and other cellular processes (Ying). Visfatin also acts as an immunomodulator by activating leukocytes and inducing the production of pro-inflammatory and anti-inflammatory cytokines (Moschen <i>et al.</i>), and there is evidence that visfatin can regulate insulin receptor signaling and insulin secretion (Brown <i>et al.</i>). Belonging to the nicotinate phosphoribosyltransferase (NAPRTase) family, Visfatin is an adipokine that is produced in adipocytes, leukocytes, and hepatocytes (Chiu <i>et al.</i>, Garten <i>et al.</i>, Kralisch <i>et al.</i>). It is active as a homodimer with each identical monomer consisting of two structural domains made up of 19 β-strands and 13 α-helices (Kim <i>et al.</i>). For consistency and reproducibility across your applications, visfatin from STEMCELL comes lyophilised with ≥90% purity, and is verified by LAL analysis to ensure endotoxin levels are ≤1,0 EU/μg protein.

UOM: 1 * 100 µG

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Proveedor: Thermo Fisher Scientific

Descripción: A non-selective phosphodiesterase inhibitor

FDS Certificados

Numero del catalogo: (EHERC16813610)

Proveedor: EHRENSTORFER

Descripción: Riboflavine-5'-phosphate sodium salt

UOM: 1 * 0,25 g

Certificados Promoción

Numero del catalogo: (PROOBP459)

Proveedor: LGC Standards PROMOCHEM

Descripción: Riboflavine-5'-phosphate sodium salt

UOM: 1 * 50 mg

Certificados Promoción

Proveedor: MP Biomedicals

Descripción: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.