Esta buscando: bile

Numero del catalogo: (OXOITV5009E)

Proveedor: THERMO FISHER DIAGNOSTICS GMBH

Descripción: Bile green 2% agar, Estándar: -,: Aplicación: Salmonella

UOM: 1 * 50 UN

Promoción

Numero del catalogo: (1.16122.0500)

Proveedor: Merck

Descripción: For the enumeration, detection and identification of β-glucuronidase positive <i>Escherichia coli</i> from food and feeding stuff as well as from environmental samples in the area of food production and food handling.

UOM: 1 * 500 g

MSDS Certificados Promoción

Proveedor: THERMO FISHER DIAGNOSTICS

Descripción: Bile salts No 3, 250 g

Numero del catalogo: (ENZOALX801035C100)

Proveedor: ENZO LIFE SCIENCES

Descripción: Bile Salts
Bile salts are important physiological agents that serve a number of functions, including absorption, solubilization, transport and secretion of lipids. In the liver, they participate in the generation of Bile flow and the secretion of cholesterol and phospholipids, such as phosphatidylcholine. When released into the intestine, they facilitate the uptake of cholesterol, fat-soluble vitamins and other lipids. Moreover, the biosynthesis of Bile acids from cholesterol is the most significant pathway for the elimination of cholesterol from the body. However, because of their detergent properties, Bile acids are inherently cytotoxic and disruptions in their normal transport or secretion can result in a variety of pathophysiological conditions.

BSEP
Bile formation is an important function of the liver. It is mediated by hepatocytes which generate Bile flow within the Bile canaliculi by continuous vectorial secretion of Bile salts and other solutes across their canalicular (apical) membrane. Bile secretion is mediated by several ATP-binding cassette (ABC) transporters located in the canalicular membrane of hepatocytes. Among these ABC transporters, the Bile salt export pump (BSEP or ABCB11) represents the primary, if not sole transport system for the canalicular excretion of Bile salts. Bile secretory failure results in cholestasis and progressive familial intrahepatic cholestasis (PFIC) in infancy represents a group of inherited cholestatic diseases that are classified into three subtypes. One of these subtypes, PFIC II, is associated with mutations in the BSEP gene. PFIC patients with mutations in the BSEP gene have normal γ-glutamyltransferase activity, low concentrations of Bile salts in Bile, and an absence of Bile duct proliferation. Additionally, human obesity is associated with altered cholesterol homeostasis including increased production and turnover, as well as secretion of excess cholesterol from the liver into Bile.

BSEP is a multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-ancoring domain and an ATP-binding cassette (ABC) domain. The membrane-anchoring domain is composed of six helixes buried in the lipid bilayer of the plasma membrane and the ATP binding ABCs are exposed to the cytosol. The membrane-anchoring domain helixes are thought to form channels spanning the plasma membrane.

UOM: 1 * 100 µG

New Product Promoción

Proveedor: VWR Chemicals

Descripción: Dehydrated culture media in small sachets ready to make up exactly 500 ml of medium.

Numero del catalogo: (BOSSBS-5040R-CY5.5)

Proveedor: Bioss

Descripción: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

UOM: 1 * 100 µl

Promoción

Proveedor: VWR Chemicals

Descripción: Para diferentes usos en microbiología.

MSDS Certificados

Proveedor: VWR Chemicals

Descripción: Los ingredientes utilizados para preparar los medios de cultivo son muy importantes porque los resultados en última instancia dependen de la calidad de estos compuestos. Las materias primas se deben conservar entre 10-30 °C, a menos que se indique lo contrario, en sus envases cerrados en un entorno seco.

Numero del catalogo: (P11203ZA)

Proveedor: VWR Chemicals

Descripción: Environmental Petri plates 90 mm for active and passive air monitoring in pharmaceutical industries.

UOM: 1 * 20 UN

MSDS Certificados Promoción

Numero del catalogo: (USBIG8600-03L)

Proveedor: US Biological

Descripción: Anti-G Protein Coupled Bile Acid Receptor 1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promoción

Proveedor: VWR Chemicals

Descripción: Para varias aplicaciones microbiológicas.

MSDS Certificados Promoción

Numero del catalogo: (USBIG8600-03H)

Proveedor: US Biological

Descripción: Anti-G Protein Coupled Bile Acid Receptor 1 Mouse Monoclonal Antibody [clone: 7H236]

UOM: 1 * 100 µG

Promoción

Proveedor: THERMO FISHER DIAGNOSTICS

Descripción: Bile esculin agar, 500 g, Aplicación: Selective media, Selectivo para: Enterococci, Estándar: -

Numero del catalogo: (BOSSBS-2128R-HRP)

Proveedor: Bioss

Descripción: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-5040R-CY7)

Proveedor: Bioss

Descripción: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-5040R-FITC)

Proveedor: Bioss

Descripción: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

UOM: 1 * 100 µl

Promoción