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Product Image-CAYM10010854-96

SREBP-1 transcription factor assay kit

Numero del catalogo: (CAYM10010854-96)
Proveedor: Cayman Chemical
Descripción: A 96-well assay for measurement of SREBP-1.
UOM: 1 * 1 KIT
Image Unavailable-CAYM460107-1

Estaño (II) cloruro dihidrato

Numero del catalogo: (CAYM460107-1)
Proveedor: Cayman Chemical
Descripción: Estaño (II) cloruro dihidrato
UOM: 1 * 1 UN
Image Unavailable-CAYM10011055-250

4-Fenil-1,2,3-tiadiazol ≥98%

Numero del catalogo: (CAYM10011055-250)
Proveedor: Cayman Chemical
Descripción: Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolises substituted amines, CYP2E1 metabolises various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 µM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner.
UOM: 1 * 250 mg
Image Unavailable-CAYM81565-1

Peroxynitrite Na in sodium hydroxide solution

Numero del catalogo: (CAYM81565-1)
Proveedor: Cayman Chemical
Descripción: Peroxynitrite is formed in vivo by the reaction of NO with superoxide. It is a powerful oxidizing agent that can initiate lipid peroxidation, oxidize sulfhydryls, and nitrate the aromatic residues of proteins.
UOM: 1 * 1 mL
Image Unavailable-CAYM53400-100

(12Z)-9,10-Dihydroxy-12-octadecenoic acid ≥98.0%

Proveedor: Cayman Chemical
Descripción: Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation and apoptosis are features of leukotoxin toxicity. In renal phydrolysesroximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

Image Unavailable-CAYM16104-1

Anti-GPR41 Rabbit Polyclonal Antibody

Numero del catalogo: (CAYM16104-1)
Proveedor: Cayman Chemical
Descripción: Anti-GPR41 Rabbit Polyclonal Antibody
UOM: 1 * 1 UN
Product Image-CAYM25922-100

Anti-STING mouse monoclonal antibody [clone: 8E7]

Numero del catalogo: (CAYM25922-100)
Proveedor: Cayman Chemical
Descripción: Anti-STING mouse monoclonal antibody [clone: 8E7]
UOM: 1 * 100 µG
Image Unavailable-CAYM14499-25

Blasticidin S hydrochloride ≥95%, crystalline solid

Proveedor: Cayman Chemical
Descripción: Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from <i>S. griseochromogenes</i>. The structure of the pentahydrate form is determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule.

FDS

Image Unavailable-CAYM14612-5

7-Dehydrocholesterol ≥90%, crystalline solid

Proveedor: Cayman Chemical
Descripción: 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.

Image Unavailable-CAYM24106-500

ML RR-S2 CDA (ammonium salt) ≥98%

Proveedor: Cayman Chemical
Descripción: ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.

Image Unavailable-CAYM15935-1

Taurodeoxycholic acid sodium salt ≥95%

Proveedor: Cayman Chemical
Descripción: Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally. Serum levels of taurodeoxycholic acid increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.

Image Unavailable-CAYM36700-25

3,6-Bis(4-(bis(2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione ≥95%

Numero del catalogo: (CAYM36700-25)
Proveedor: Cayman Chemical
Descripción: 3,6-Bis(4-(bis(2-hydroxydodecyl)amino)butyl)piperazine-2,5-dione ≥95%
UOM: 1 * 25 mg

New Product


Image Unavailable-CAYM14122-5

CID-2858522 ≥98%

Proveedor: Cayman Chemical
Descripción: CID-2858522 ≥98%

Image Unavailable-CAYM13379-1

5-Bromo-3-phenylsalicylic acid

Proveedor: Cayman Chemical
Descripción: 5-Bromo-3-phenylsalicylic acid

Image Unavailable-CAYM10010302-50

Bencimidazol

Proveedor: Cayman Chemical
Descripción: Bencimidazol

Image Unavailable-CAYM14320-50

Azul brillante Coomassie G-250

Proveedor: Cayman Chemical
Descripción: Azul brillante Coomassie G-250

Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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