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Image Unavailable-BOSSBS-12359R-A555

Anti-DMP1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numero del catalogo: (BOSSBS-12359R-A555)
Proveedor: Bioss
Descripción: DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2990R-HRP

Anti-CITED1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numero del catalogo: (BOSSBS-2990R-HRP)
Proveedor: Bioss
Descripción: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
UOM: 1 * 100 µl
Product Image-UVEX8543.8/48

Zapatos de seguridad ESD, con cordones, uvex 1, 8543

Proveedor: UVEX
Descripción: Zapato de seguridad multifuncional, extremadamente ligero y fabricado con una parte superior de microterciopelo transpirable y perforado de alta tecnología, lengüeta y cuello suavemente acolchados, además de una suela de PUR de doble densidad (resistente al aceite y a la gasolina, y antiestática) sin inhibidores de la humedad de la laca, como las siliconas o los ftalatos.

Product Image-BOSSBS-2990R

Anti-CITED1 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-2990R)
Proveedor: Bioss
Descripción: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
UOM: 1 * 100 µl
Product Image-UVEX6509.2/51

Botas de seguridad ESD, con cordones, uvex 2, 6509

Proveedor: UVEX
Descripción: Zapato de seguridad sin metal, extremadamente ligero, flexible y multifuncional, fabricado con una parte superior de microvelour de alta tecnología perforada y transpirable, lengüeta y cuello suavemente acolchados, y una suela PUR de doble densidad (resistente al aceite y la gasolina, y antiestática) sin inhibidores de la humedad de la laca, como las siliconas o los ftalatos.

Image Unavailable-BOSSBS-12359R-FITC

Anti-DMP1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numero del catalogo: (BOSSBS-12359R-FITC)
Proveedor: Bioss
Descripción: DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12359R-A680

Anti-DMP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numero del catalogo: (BOSSBS-12359R-A680)
Proveedor: Bioss
Descripción: DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesised by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate. The loss of DMP-1 can result in hypomineralized bone.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12359R-CY3

Anti-DMP1 Rabbit Polyclonal Antibody (Cy3®)

Numero del catalogo: (BOSSBS-12359R-CY3)
Proveedor: Bioss
Descripción: DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
UOM: 1 * 100 µl
Product Image-UVEX8542937

Zapatos de seguridad ESD, Velcro®, uvex 1, 8542

Proveedor: UVEX
Descripción: Zapato de seguridad sin metal, extremadamente ligero, flexible y multifuncional, fabricado con una parte superior de microterciopelo transpirable y perforado de alta tecnología, una lengüeta y un cuello acolchados y una suela de PUR de doble densidad (resistente al aceite y a la gasolina, y antiestática) sin inhibidores de la humedad de la laca, como las siliconas o los ftalatos.

Image Unavailable-BNC940141-500

Anti-ALPI Mouse Monoclonal Antibody (CF594) [clone: V17.1]

Proveedor: Biotium
Descripción: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Image Unavailable-BNC040597-500

Anti-ALPI Mouse Monoclonal Antibody (CF405S) [clone: ALP/597]

Proveedor: Biotium
Descripción: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Image Unavailable-BNC470597-500

Anti-ALPI Mouse Monoclonal Antibody (CF647) [clone: ALP/597]

Proveedor: Biotium
Descripción: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Image Unavailable-BNUM0141-50

Anti-ALPI Mouse Monoclonal Antibody (Purified, BSA-free) [clone: V17.1]

Numero del catalogo: (BNUM0141-50)
Proveedor: Biotium
Descripción: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
UOM: 1 * 50 µl
Image Unavailable-BOSSBS-12359R-A647

Anti-DMP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numero del catalogo: (BOSSBS-12359R-A647)
Proveedor: Bioss
Descripción: DMP-1 is a member of the small integrin ligand N-linked glycoprotein family. It is important for the mineralization of bone and dentin. DMP-1 is expressed in bone, tooth and hypertrophic cartilage. It is synthesized by preosteoblasts and contains a large number of acidic domains. DMP-1 localizes to the nucleus of undifferentiated osteoblasts where it functions as a transcriptional regulator for osteoblast-specific gene activation and induces osteoblast differentiation. During osteoblast maturation, DMP-1 undergoes a conformational change and becomes phosphorylated by casein kinase II in response to an influx of calcium ions to the nucleus. DMP-1 is then exported to the extracellular matrix (ECM) where it regulates the nucleation of hydroxyapatite and the formation of calcified tissue. DMP-1 is proteolytically processed into N- and C-terminal fragments in the ECM of bone and dentin. The protein has also been identified in bone as a high molecular weight proteoglycan comprised of the N-terminal DMP-1 fragment and chondroitin sulfate.The loss of DMP-1 can result in hypomineralized bone.
UOM: 1 * 100 µl
Product Image-113-1836

VWR®, Batas resistentes a productos químicos de poliéster/Hydro-Tec, reutilizables

Proveedor: VWR Collection
Descripción: Estas batas antiestáticas están fabricadas de un 99% de fibras de poliéster con acabado 1% Hydro-Tec (tratado con carbono), lo que permite un resultado extremadamente duradero y excelente para repeler el polvo, aceites, productos químicos y agua. Todas las batas tienen cuello alto, dos bolsillos laterales y un bolsillo en el pecho, los tres protegidos con una solapa.

Product Image-UVEX8511.8/38

Zapatos de seguridad ESD, con cordones, uvex 1 x-tended support, 8511

Proveedor: UVEX
Descripción: Zapato de seguridad sin metal, extremadamente ligero, flexible y multifuncional, fabricado con una parte superior de microterciopelo transpirable y perforado de alta tecnología, una lengüeta y un cuello acolchados y una suela de PUR de doble densidad (resistente al aceite y a la gasolina, y antiestática) sin inhibidores de la humedad de la laca, como las siliconas o los ftalatos.

Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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