Esta buscando: SMCC+(N-Succinimidyl+4-(N-Maleimidomethyl)cyclohexanecarboxylate)

Proveedor: TCI

Descripción: SMCC (N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate) ≥98.0% (by HPLC)

Numero del catalogo: (BC20)

Proveedor: G-Biosciences

Descripción: Succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate Heterobifunctional Cross Linkers.

UOM: 1 * 100 mg

Promoción

Proveedor: Apollo Scientific

Descripción: Primary amine and Sulphhydryl reactive, Enzyme antibody conjugation.

Numero del catalogo: (PIERA35394)

Proveedor: Thermo Fisher Scientific

Descripción: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

UOM: 1 * 10 mg

Promoción

Numero del catalogo: (573114-100)

Proveedor: Merck Millipore (Calbiochem‎)

Descripción: Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.
Reacts with primary amines and sulfhydryl groups.

UOM: 1 * 100 mg

Certificados Promoción

Numero del catalogo: (PIER22360)

Proveedor: Thermo Fisher Scientific

Descripción: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

UOM: 1 * 50 mg

MSDS Certificados Promoción

Proveedor: AAT BIOQUEST INC

Descripción: SMCC is a non-cleavable and membrane permeable crosslinker with a spacer arm of 8.3 Å. It contains an amine-reactive succinimidyl ester (SE) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7 to 9 to form stable amide bonds. Maleimides react with sulfhydryl groups at pH 6.5 to 7.5 to form stable thioether bonds. The SE group of SMCC is reacted with lysine residues on the carrier protein, converting them to reactive maleimides. SMCC is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.

New Product

Proveedor: SIGMA-ALDRICH MICROSCOPY

Descripción: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt,powder (Sulfo-SMCC)

Proveedor: TCI

Descripción: Sulpho-SMCC (3-Sulpho-N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt)

Proveedor: Thermo Scientific

Descripción: Sulpho-SMCC (3-Sulpho-N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt) ≥97%

MSDS Certificados

Numero del catalogo: (TCIAS0881-25MG)

Proveedor: TCI

Descripción: LC-SMCC (N-Succinimidyl 6-[[4-(N-Maleimidomethyl)cyclohexyl]carboxamido]hexanoate) ≥98.0% (by HPLC)

UOM: 1 * 25 mg

Promoción

Numero del catalogo: (BC23)

Proveedor: G-Biosciences

Descripción: Ideal for enzyme-antibody crosslinking.

UOM: 1 * 100 mg

Promoción

Numero del catalogo: (APOSBICL207-100MG)

Proveedor: Apollo Scientific

Descripción: Primary amine & Sulphhydryl reactiveEnzyme-antibody conjugation -Stable maleimide groupRef: Hushida, S. et al (1984) J.Applied Biochem. 56,56-63

UOM: 1 * 100 mg

Promoción

Numero del catalogo: (PIERA39268)

Proveedor: Thermo Fisher Scientific

Descripción: Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).

UOM: 1 * 20 mg

Promoción

Proveedor: Thermo Fisher Scientific

Descripción: Thermo Scientific Pierce Premium Grade Sulfo-SMCC is our highest quality formulation of amine-to-sulfhydryl crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

Numero del catalogo: (AATB4503)

Proveedor: AAT BIOQUEST INC

Descripción: Compared to SMCC and sulfo-SMCC, SMCC Plus has enhanced water solubility and crosslinking efficiency.

UOM: 1 * 5 mg

New Product Promoción